Detection of Viruses Using Toehold Switches
Toehold switches, as an engineered RNA element, are capable of manipulating the translation of reporter genes. Based on this feature, toehold switches have been widely used in virus detection. At CD BioSciences, the toehold switches technology platform has been established and has been applied to the detection of various viruses. The following is a brief description of the application of toehold switches for coronavirus, Zika virus, Ebola virus, norovirus, potato Y virus, and respiratory syncytial virus.
Detection of Coronavirus Using Toehold Switches
Coronaviruses are linear single-stranded positive-stranded RNA viruses, which are a large class of viruses that exist widely in nature. The novel coronavirus pneumonia currently sweeping the world is caused by SARS-CoV-2, which has caused great harm to the world. CD BioSciences uses the toehold switches technology platform to provide biosensor development services and detection services for coronavirus for scholars engaged in coronavirus-related research.
Detection of Zika Virus Using Toehold Switches
Zika virus is a single-stranded positive-stranded RNA virus. The virus is transmitted by mosquitoes and is prone to outbreaks of Zika virus infection in tropical and economically underdeveloped areas. The virus can cause "microcephaly" in babies. CD BioSciences uses the toehold switches technology platform to provide Zika virus-specific biosensor development services and detection services for those engaged in Zika virus-related research.
Detection of Ebola Virus Using Toehold Switches
Ebola virus is a single-stranded negative-stranded RNA virus. The virus is spread through the patient's blood, saliva, sweat, etc. Ebola hemorrhagic fever is one of the most virulent known infectious diseases in the world. CD BioSciences uses the toehold switches technology platform to provide biosensors development services and detection services for the Ebola virus for researchers engaged in Ebola virus-related research.
Detection of Norovirus Using Toehold Switches
Norovirus is a single-stranded, positive-sense RNA virus. The virus is mainly transmitted through fecal-oral and droplet routes, with high contagiousness and rapid transmission ability, mainly causing diarrhea in infected persons, and has become a global health problem. CD BioSciences uses the toehold switches technology platform to provide biosensors development services and detection services for norovirus for those engaged in norovirus-related research.
Detection of Potato Virus Y Using Toehold Switches
Potato virus Y is a single-stranded positive-stranded ssRNA virus, also known as tobacco vein spot virus disease. The virus has many hosts and can damage a variety of food plants and cause great economic losses. CD BioSciences uses the toehold switches technology platform to provide the biosensor development service and detection service for the potato Y virus for the researchers engaged in the potato Y virus-related research.
Detection of Respiratory Syncytial Virus Using Toehold Switches
The respiratory syncytial virus is a ubiquitous RNA virus. The virus is one of the main viruses causing lower respiratory tract infections in children under 5 years of age. CD BioSciences uses the toehold switches technology platform to provide biosensors development services and detection services for the respiratory syncytial virus for those engaged in respiratory syncytial virus-related research.
CD BioSciences has long focused on the application research of toehold switches. We can apply toehold switches to the detection of various viruses and provide you with corresponding services. If you are interested in our service based on toehold switches, please feel free to contact us .