Toehold Switch Synthesis Service

Toehold Switch Synthesis Service

Toehold switch is a synthetic RNA tool that mimics messenger RNAs and is capable of responding to homologous RNAs of any sequence to activate gene expression. And, the species switch can also be integrated into the genome for regulating endogenous genes and acting as a sensor for endogenous genes. The discovery of toehold switch accelerates the development of biotechnology tools to advance scientific and medical research. CD BioSciences, as a cutting-edge biotechnology company, focuses on toehold switch research and builds the toehold switch technology platform to provide you with professional toehold switch synthesis services.

Our Services

The chemical synthesis of toehold switch is made more difficult due to the low coupling efficiency of RNA bases, easy disassembly of the product, and the need to link reporter genes. However, at CD BioSciences, we have a first-class research team, advanced machines, and a professional toehold switch synthesis system. toehold switch synthesis service is our specialty.

We first evaluate your toehold switch sequences against specific trigger RNA sequences, and then sequences that meet the requirements are synthesized in our clean experiments, and toehold switch sequences that do not meet the requirements are optimized by us before being synthesized.

Toehold Switch RNA Modifications

Depending on the purpose of your research, we are able to modify your toehold switch RNA in different ways.

• If you need to develop a diagnostic test, we will attach a fluorescent reporter molecule to the toehold switch for you.
• If you need to develop biosynthesis tools, we will connect you to a synthetic protein gene on the toehold switch.
• If you need to develop gene therapies, we will link specific gene fragments for you on the toehold switch.

Customer to Provide

We offer a one-stop service from toehold switch design to synthesis, and you have the following options.

• You can choose to provide us with information such as trigger RNA sequence, research objectives, and host cell type, and we will provide you with toehold switch design, optimization, and synthesis services.
• Alternatively, you can provide us with the sequence of the toehold switch to be synthesized, as well as the yield and purity requirements, and we will provide you with the synthesis of the toehold switch.

Delivery Content

• Certificate of analysis, quality control report.
• Synthetic toehold switches RNA lyophilized powder.
• Purity analysis report, including high-performance liquid chromatography analysis graph, mass spectrometry graph, etc.

Our Advantages

• Our services have the best cost performance, providing you with excellent services at competitive prices.
• We have a team of experienced toehold switch RNA synthesis experts to provide you with perfect technical support.
• We have strict quality requirements to ensure no contamination of RNase during toehold switch RNA synthesis.
• Our wide range of services can meet any of your requirements for toehold switch RNA, including modification, fluorescent labeling, and ligation of reporter genes.

We Are Ready to Provide

CD BioSciences is focused on providing you with a customized toehold switch synthesis service. With the advantages of the high quality, cost-effectiveness, and purity of this service, please trust us to meet any of your needs. If you are interested in this toehold switch synthesis service, please contact us directly.