Study of Genes Using Toehold Switches
Gene is the basic unit of heredity, and DNA or RNA sequences carrying genetic information control the expression of individual traits by directing protein synthesis. Genetic testing is a technique that tests DNA in blood, other body fluids, or cells. Genetic testing is important for revealing potentially disease-causing changes (mutations) in genes. Currently, toehold switches are being used in genetic testing. At CD BioSciences, we have established an advanced toehold switches technology platform and can apply this technology platform to the detection of antibiotic resistance genes and the regulation of gene expression.
Detection of Antibiotic Resistance Genes Using Toehold Switches
Antibiotic resistance genes (ARGs) can enter pathogenic bacteria through horizontal gene transfer and other methods and confer antibiotic resistance to the host, thus seriously threatening human health. Currently, ARGs have become a major problem in human and animal health. To effectively monitor ARGs, toehold switches have been used in the development of their detection tests. Biosensors based on toehold switches have been developed to efficiently detect ARGs. CD BioSciences can use the toehold switches technology platform to provide you with related services.
Regulation of Gene Expression Using Toehold Switches
Any step of gene expression can be regulated, from transcription initiation to RNA processing to post-translational modification of proteins. The regulation of gene expression is one of the central topics of modern molecular biology research. Toehold switches can be integrated into the genome to sense cellular endogenous RNAs and regulate the expression of endogenous genes. CD BioSciences can use the established toehold switches technology platform to provide you with powerful toehold switches technical support to help your research on gene expression regulation.
CD BioSciences focuses on the application research of toehold switches. We continue to enrich our knowledge and improve our capabilities and are committed to providing detection-related services for scholars engaged in ARGs research and technical support for scholars engaged in regulatory gene expression research. If you are interested in these application areas, feel free to contact us at any time.